Both of his parents are of Greek descent, and his family’s original surname, “Zanetakos”, was anglicized to “Zane” by his parents. He has an older sister, Lisa Zane, who is an actress. He also starred in the NBC film, The Case of the Hillside Stranglers (1989). in 1993, he played the Shakespearean actor “Mr. Fabian” in Tombstone, and took a starring role in Sniper. He was also nominated for a SAG award. in 1998, Zane starred in and produced I Woke Up Early The Day I Died, a silent film based on Ed Wood’s last script, intended as a parody on bad filmmaking. The same year, he also had a cameo as himself in the popular comedy Zoolander. Zane keeps busy in other parts of the entertainment industry as well.